[HTML][HTML] DNA methylation signatures of bone metabolism in osteoporosis and osteoarthritis aging-related diseases: an updated review

VV Visconti, I Cariati, S Fittipaldi, R Iundusi… - International Journal of …, 2021 - mdpi.com
… , previously identified by a genome-wide association study as a novel … bone biopsies from
postmenopausal OP women, revealing … However, these differentially methylated regions of the …

[HTML][HTML] Effect of DNA methylation on gene transcription is associated with the distribution of methylation sites across the genome in osteoarthritis

P Yi, X Xu, J Yao, B Qiu - … and Therapeutic Medicine, 2021 - spandidos-publications.com
… analysis package was used to identify differentially methylated … in the impediment of
postmenopausal osteoporosis (41). … the conventional genome-wide DNA methylation analysis, …

Alterations in DNA methylation profiles in cancellous bone of postmenopausal women with osteoporosis

Y Zhou, L Yang, H Wang, X Chen, W Jiang… - FEBS Open …, 2020 - Wiley Online Library
… of patients with osteoarthritis revealed differential methylation. In view of the … bone in bone
development, we examined genome-wide DNA methylation profiles in the cancellous bone

[HTML][HTML] Genome-wide differential methylation profiles from two terpene-rich medicinal plant extracts administered in osteoarthritis rats

Y Shin, S Subramaniyam, JM Chun, JH Jeon, JM Hong… - Plants, 2021 - mdpi.com
… medicine to treat osteoarthritis and other bone diseases—were … -related diseases, such as
OA and osteoporosis [11,12]. … shows that 929 genes contained CpGs from all three regions. …

Genomewide DNA methylation profile analysis in thoracic ossification of the ligamentum flavum

T Fan, X Meng, C Sun, X Yang, G Chen… - Journal of Cellular …, 2020 - Wiley Online Library
… , such as ankylosing spondylitis (AS), osteoporosis and osteoarthritis, show abnormal DNA
… shortlisted the differentially methylated GO terms functionally related to bone development, …

[HTML][HTML] The methylation pattern for knee and hip osteoarthritis

Z Wu, L Shou, J Wang, T Huang, X Xu - Frontiers in Cell and …, 2020 - frontiersin.org
… the methylation pattern in knee and hip osteoarthritis, we analyzed the methylation profiles
in … These findings highlight the importance of the separation of OA researches from skeletal

[HTML][HTML] Enrichment of genomic pathways based on differential DNA methylation profiles associated with knee osteoarthritis pain

S Montesino-Goicolea, L Meng, A Rani, Z Huo… - Neurobiology of Pain, 2022 - Elsevier
… IPA revealed that pain-related DMRs were enriched across … was to identify differentially
methylated CpG regions and their … , maintenance, and repair of bone, cartilage, and other soft …

[HTML][HTML] Osteoarthritis year in review: genetics, genomics, epigenetics

A Ratneswaran, M Kapoor - Osteoarthritis and cartilage, 2021 - Elsevier
… ) scans, identified eight bone area variants associated with hip or … showed robust genome-wide
significance between a DNA … was published, revealing subpopulations of chondrocytes …

Integrative analysis of genome-wide association studies and DNA methylation profile identified genetic control genes of DNA methylation for kashin-beck disease

P Li, C Wu, X Guo, Y Wen, L Liu, X Liang, Y Du… - Cartilage, 2021 - journals.sagepub.com
… of cartilage in osteoarthritis (OA) patients and healthy controls… Further comparing the
differently methylated genes with KBD … , including osteopenia and osteoporosis. Therefore, more …

A road map for understanding molecular and genetic determinants of osteoporosis

TL Yang, H Shen, A Liu, SS Dong, L Zhang… - Nature Reviews …, 2020 - nature.com
… In this Review, we highlight findings from genome-wide … of human bone detected 241
differentially methylated CpG … extent cells from osteoarthritis bone resemble normal bone cells. …